Cannabinoids - (not really neurotransmitters)

Endogenous ligand


Neurotransmitter family

fatty acid

Most common sites of action (in the nervous system), and action exerted at those sites (excitatory/inhibitory/modulatory?)

striatum - tends to inhibit smooth muscle contraction
there are receptors all over the nervous system, though

Receptors (type, differences in signaling depending on receptor?)

metabotropic canabinoid receptors (CB1 and CB2)

Mechanism to stop signaling

hydrolysis in the synapse

Behavioral outcomes of activation of this system

pain reduction
emotional regulation
short term memory deficit
movement inhibition