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  1. page Norepinephrine edited Norepinephrine {http://www.biocompare.com/images/bc/006/ArticleImages/MDCSBSN_assa_1.jpg} Gl…

    Norepinephrine
    {http://www.biocompare.com/images/bc/006/ArticleImages/MDCSBSN_assa_1.jpg}
    Glutamate-Neurotransmitter familyNeurotransmitter family
    Monoamine
    (view changes)
  2. page Cannabinoids edited Cannabinoids - (not really neurotransmitters) Endogenous ligand anandamide Glutamate-Neurotr…

    Cannabinoids - (not really neurotransmitters)
    Endogenous ligand
    anandamide
    Glutamate-Neurotransmitter familyNeurotransmitter family
    cannabinoid - fattyfatty acid
    Glutamate-Most common sites of action, and action exerted at those sites (excitatory/inhibitory/modulatory?)Acetylcholine-Most common sites of action, and action exerted at those sites (excitatory/inhibitory/modulatory?)Most common sites of action (in the nervous system), and action exerted at those sites (excitatory/inhibitory/modulatory?)
    striatum - tends to inhibit smooth muscle contraction
    there are receptors all over the nervous system, though
    Glutamate-Receptors (type, differences in signaling depending on receptor?)Acetylcholine-Receptors (type, differences in signaling depending on receptor?)Receptors (type, differences in signaling depending on receptor?)
    metabotropic canabinoid receptors (CB1 and CB2)
    Glutamate-Mechanism to stop signalingAcetylcholine-Mechanism to stop signalingMechanism to stop signaling
    hydrolysis in the synapse
    Glutamate-Behavioral outcomes of releaseAcetylcholine-Behavioral outcomes of releaseBehavioral outcomes of activation of this system
    reward
    (view changes)
  3. page Epinephrine edited ... Epinephrine Glutamate-Neurotransmitter familyNeurotransmitter family catecholamine catecho…
    ...
    Epinephrine
    Glutamate-Neurotransmitter familyNeurotransmitter family
    catecholaminecatecholamine-monoamine
    Glutamate-Most common sites of action, and action exerted at those sites (excitatory/inhibitory/modulatory?)Acetylcholine-Most common sites of action, and action exerted at those sites (excitatory/inhibitory/modulatory?)Most common sites of action, and action exerted at those sites (excitatory/inhibitory/modulatory?)
    ...
    adrenal cortex - generally acts in the peripheral nervous system
    acts on nearly all body tissues
    excitatory and inhibitorygenerally excitatory
    Glutamate-Receptors (type, differences in signaling depending on receptor?)Acetylcholine-Receptors (type, differences in signaling depending on receptor?)Receptors (type, differences in signaling depending on receptor?)
    adrenergic receptors
    ...
    reuptake
    Glutamate-Behavioral outcomes of releaseAcetylcholine-Behavioral outcomes of releaseBehavioral outcomes of release
    fight or flightsimilar to norepinephrine - activation of sympathetic nervous system; attention, arousal, preparation to respond to a stimulus
    (view changes)
  4. page Norepinephrine edited ... Monoamine Glutamate-Most common sites of action, and action exerted at those sites (excitato…
    ...
    Monoamine
    Glutamate-Most common sites of action, and action exerted at those sites (excitatory/inhibitory/modulatory?)Acetylcholine-Most common sites of action, and action exerted at those sites (excitatory/inhibitory/modulatory?)Most common sites of action, and action exerted at those sites (excitatory/inhibitory/modulatory?)
    The release of norepinephrine is a result of the activation (excitation) of the sympathetic system; it prepares the body for vigorous activities, stress and emergencies (fight or flight response).
    The
    norepinephrine system
    ...
    brain including:
    -amygdala
    -cingulate gyrus
    ...
    -neocortex
    -spinal cord
    -striatum
    -thalamus

    -thalamus

    Glutamate-Receptors (type, differences in signaling depending on receptor?)Acetylcholine-Receptors (type, differences in signaling depending on receptor?)Receptors (type, differences in signaling depending on receptor?)
    ...
    alpha receptors.
    http://www.elmhurst.edu/~chm/vchembook/663adrenergic.html
    Glutamate-Mechanism to stop signalingAcetylcholine-Mechanism to stop signalingMechanism to stop signaling
    reuptake
    Glutamate-Behavioral outcomes of releaseAcetylcholine-Behavioral outcomes of releaseBehavioral outcomes of release
    The release of norepinephrine is a result of the activation (excitation) of the sympathetic system; it prepares the body for vigorous activities, stress and emergencies (fight or flight response).
    general arousal, increased attention and focus

    Drugs that act on this system (where? what do they do? what is the behavioral outcome?)
    some antidepressants
    (view changes)
  5. page Dopamine edited ... Dopamine Glutamate-Neurotransmitter familyNeurotransmitter family Catecholamine - monoamine…
    ...
    Dopamine
    Glutamate-Neurotransmitter familyNeurotransmitter family
    Catecholamine - monoamine
    Glutamate-Most common sites of action, and action exerted at those sites (excitatory/inhibitory/modulatory?)Acetylcholine-Most common sites of action, and action exerted at those sites (excitatory/inhibitory/modulatory?)Most common sites of action, and action exerted at those sites (excitatory/inhibitory/modulatory?)
    ...
    Area (Brain), Excitatory
    generally neuromodulatory - tends to lead to excitation by inhibiting inhibitory signals.

    Glutamate-Receptors (type, differences in signaling depending on receptor?)Acetylcholine-Receptors (type, differences in signaling depending on receptor?)Receptors (type, differences in signaling depending on receptor?)
    ...
    D4, D5 - all metabotropic
    Glutamate-Mechanism to stop signalingAcetylcholine-Mechanism to stop signalingMechanism to stop signaling
    Reuptake via hethe dopamine transporter
    Glutamate-Behavioral outcomes of releaseAcetylcholine-Behavioral outcomes of releaseBehavioral outcomes of release
    ...
    reward, cognition
    Drugs that act on this system (where? what do they do? what is the behavioral outcome?)
    Cocaine, amphetamine; Enjoyment and
    (view changes)
  6. page GABA edited ... Amino Acid Glutamate-Most common sites of action, and action exerted at those sites (excitat…
    ...
    Amino Acid
    Glutamate-Most common sites of action, and action exerted at those sites (excitatory/inhibitory/modulatory?)Acetylcholine-Most common sites of action, and action exerted at those sites (excitatory/inhibitory/modulatory?)Most common sites of action, and action exerted at those sites (excitatory/inhibitory/modulatory?)
    ...
    nervous system - generally inhibitory. Is the major inhibitory neurotransmitter in the CNS.
    Medium spiny cells act as inhibitory GABAergic cells in CNS.
    Acts excitatory in insects and activates synapses between nerves and muscles.
    ...
    - excitatory effects,effects during development, regulates growth
    Glutamate-Receptors (type, differences in signaling depending on receptor?)Acetylcholine-Receptors (type, differences in signaling depending on receptor?)Receptors (type, differences in signaling depending on receptor?)
    GABA receptors(Gaba A and Gaba B)
    (view changes)
  7. page Glutamate edited ... Reuptake via the glutamate transporter - located in the presynaptic neuron and the glial cells…
    ...
    Reuptake via the glutamate transporter - located in the presynaptic neuron and the glial cells
    Acetylcholine-Behavioral outcomes of releaseBehavioral outcomes of release
    TheGenerally activation of a system. The release of
    Drugs that act on this system (where? what do they do? what is the behavioral outcome?)
    PCP and Ketamine act on this system by being non-competitive antagonists at the NMDA glutamate receptors, which blocks binding of glutamate. Ketamine reduces depression in patients. In PCP can invoke schizophrenia-like symptoms as in strong auditory hallucinations, depersonalization, and delusions.
    (view changes)
  8. page Glutamate edited ... Mostly acts on the receptors of neurons like the NMDA glutamate receptor and is always excitat…
    ...
    Mostly acts on the receptors of neurons like the NMDA glutamate receptor and is always excitatory and leads to the activation of the cell and/or neuron. The release of glutamate typically happens throughout the brain but is more effective on the glutamageric synapses in the hippocampus and neocortex due to its long-term potentiation.
    Acetylcholine-Receptors (type, differences in signaling depending on receptor?)Receptors (type, differences in signaling depending on receptor?)
    ...
    on the AMPA receptors, NMDA receptors,
    Acetylcholine-Mechanism to stop signalingMechanism to stop signaling
    Receptor desensitization.Reuptake via the glutamate transporter - located in the presynaptic neuron and the glial cells
    Acetylcholine-Behavioral outcomes of releaseBehavioral outcomes of release
    The release of glutamate in to the synapse triggers Long Term Potentiation, learning, and the creation of memory. Disruption of glutamate can cause depression.
    (view changes)

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